Editorial in J Hypertension (2012; 30:874-876)
Should ambulatory blood pressuremonitoring be mandatory for future studies in resistant hypertension: a perspective by Michael Doumas, Panagiota Anyfanti, and George Bakris
Recent technologic advances rekindled interventional management of resistant hypertension, either by carotid
baroreceptor activation or renal sympathetic denervation. Interventional techniques result in impressive falls in office blood pressure (BP); however, ambulatory BP reductions are rather modest. This disparity between office and ambulatory BP reductions is observed with antihypertensive drugs, but at a much lower degree. Available explanations are not convincing, therefore, we propose that sympathetic overactivity may partially explain this divergence. Further studies are needed to prove or disprove our hypothesis.